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The evaluation of clinical effect of locally delivered minocycline hydrochloride, doxycycline irrigation, saline irrigation in the treatment of periodontal abscess patients. A Retrospective Study.

The evaluation of clinical effect of locally delivered minocycline hydrochloride, doxycycline irrigation, saline irrigation in the treatment of periodontal abscess patients. A Retrospective Study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0006551
Enrollment
63
Registered
2021-09-07
Start date
2021-05-26
Completion date
Unknown
Last updated
2021-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Yonsei University Health System, Dental Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: . Patients who have the first or second molars with periodontal pocket depth of 6 mm or more, bleeding or purulent exudate during probing, loss of alveolar bone on the periapical radiograph, and clinically found ovoid edema in the gingiva along the side of the root in normal body temperature (36.4~36.7°C).

Exclusion criteria

Exclusion criteria: ? Those taking medications that can affect periodontal disease (calcium channel blockers, phenytoin, cyclosporine, warfarin, aspirin, clopidogrel) ?Uncontrolled hypertension, diabetes, heart disease, and smokers (excluding those who smoked 10 years ago) ? Pregnant or lactating women, and patients with a history of tetracycline allergy. ? In case of other causes than periodontitis, such as intragingival foreign body impaction, endodontic lesions, or tooth cracks ? When the extent of the abscess includes adjacent teeth ? Those who took antibiotics one month before treatment or took antibiotics and anti-inflammatory drugs after treatment ? Those with cervical lymphadenitis added after treatment

Design outcomes

Primary

MeasureTime frame
probing depth

Secondary

MeasureTime frame
Plaque index (PI], bleeding on probing (BOP), gingival recession (GR), clinical attachment level (CAL), Periotest value (PTV)

Countries

Korea, Republic of

Contacts

Public ContactDong Yeol Jung

Yonsei University Health System, Dental Hospital

ukyos@hanmail.net+82-32-566-2080

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026