Optimizing the dose of intrathecal morphine in patients undergoing laparoscopic donor hepatectomy; a randomized non-inferiority trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0006526

Enrollment

Registered

2021-09-01

Start date

2021-08-29

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Drug name : Morphine Dose : 300mcg or 400mcg single shot before the surgery Intrathecal injection difference between group : morphine dose

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who undergo living donor hepatectomy for liver transplantation ASA physical status I or II

Exclusion criteria

Exclusion criteria: ASA physical status III or more Severe impaired coagulation profile (equal or more than INR 1.5 last coagulation test before the surgery) Patients who have unstable coronary disease or Congestive heart failure or Arrhythmia or cardiomyopathy Patients who have cerebrovascular disease Patients who have systemic infection or local infection on lumbar Chronic pain patients Patients who don't understand about study or refuse the study Patients who have history of severe psychological disease

Design outcomes

Primary

Measure	Time frame
Pain score (representing by 11-points Numerous Rating Scale)	—

Secondary

Measure	Time frame
Pain score (representing by 11-points Numerous Rating Scale);Opioid consumption;Nausea, Vomiting, Pruritus;Pain relief satisfaction;Sleep satisfaction;First gas-out time;Hypoventilation, Hypotension, Headache;The questionaire of QoR-15 score before and after the surgery	—

Countries

Korea, Republic of

Contacts

Public ContactJoan Seungwon Lee

Samsung Medical Center

seungwon0209.lee@samsung.com+82-2-3410-0369

Outcome results