None listed
Conditions
Interventions
None listed
Sponsors
Dong-A University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Male or female over 19 years of age and under 70 years of age 2) Laryngeal reflux (LPR) patients with reflux observation score (RFS) of 7 or more and reflux symptom index (RSI) of 13 or more character 3) Those who agreed to participate in this study and voluntarily signed the written consent 4) Those without dementia or cognitive impairment
Exclusion criteria
Exclusion criteria: 1) Those with a history of allergic symptoms (rash, fever, itching, etc.) or hypersensitivity reactions to this research drug 2) Those with confirmed malignant tumor or infection of the larynx 3) Those taking Atazanavir or Rilpivirine 4) 3 months of study participation with another proton pump inhibitor (PPI) or H2 receptor aatagonist (H2RA) those who took it within 5) Those with a history of Zollinger-Ellison syndrome (ZES), alcoholism, or substance abuse 6) Pregnant and lactating women 7) Those who have participated in a clinical trial within 6 months of participating in the study 8) Those who are judged inappropriate by the researcher to participate in the research for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of improvement in the reflux symptom index (RSI) of the ilaprazole group and the esomeprazole group | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of the improvement in the reflux findings score (RFS) between the ilaprazole group and the esomeprazole group | — |
Countries
Korea, Republic of
Contacts
Public ContactDong Kun Lee
Dong-A University Hospital
Outcome results
None listed