None listed
Conditions
Interventions
Others(blood sampling and ex-vivo diagnosis) : This study will be conducted with a single arm, and the subjects will have a total of three blood samplings for study. The collection time is 1) before t
Sponsors
Pusan National University Yangsan Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) 19 years old or older 2) Primary cancer site as the following head and neck cancer: oral cavity, oropharynx, larynx and hypopharynx, nasal cavity and paranasal sinus, nasopharynx 3) Histological diagnosis is squamous cell carcinoma (however, including cases with similar clinical course comparable to squamous cell carcinoma, for example, undifferentiated cancer) 4) Patients who have no distant metastasis 5) Patients whose curative treatment is determined as radiotherapy or chemoradiation 6) A person who signed written informed consent after voluntarily understanding the clinical research
Exclusion criteria
Exclusion criteria: 1) Diagnosis of salivary gland cancer 2) Histologic type is not squamous cell carcinoma 3) Patients scheduled for radical surgery 4) Patients with distant metastasis 5) Patients who underwent major surgery requiring general anesthesia within 4 weeks of study registration 6) Those with a history of other malignancies within the past 3 years (excluding cured skin basal cell carcinoma, cervical epithelial cancer, superficial bladder cancer, and differentiated thyroid cancers)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CTC detection rate before starting CRT | — |
Secondary
| Measure | Time frame |
|---|---|
| CTC detection rate in the end of CRT;CTC detection rate after 8-12 weeks after CRT completion;CTC detection rate in the detection of disease progression | — |
Countries
Korea, Republic of
Contacts
Public ContactSo Yeon Oh
Pusan National University Yangsan Hospital
Outcome results
None listed