None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: elderly patient, more than 65 years, undergoing total knee arthroplasty
Exclusion criteria
Exclusion criteria: 1) psychotic disorder (schizophrenia, seizure, Parkinson's disease, dementia) 2) severe bradycardia (<45 bpm), sick sinus syndrome, 2nd or 3rd degree AV block) 3) severe hepatic dysfunction 4) severe renal dysfunction 5) recent history of stroke within 6 months 6) alcohol or other drug abuse 7) difficulty of communication 8) ASA PS 4 or more 9) preoperative K-MMSE score less than 20
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Develoment of postoperative delirium | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of postoperative delirium | — |
Countries
Korea, Republic of
Contacts
Jeonbuk National University Hospital