None listed
Conditions
Interventions
Dietary Supplement : Test supplement: Maekmundong extract 1,000 mg/day
Placebo supplement: placebo
Take orally for 4 weeks, 2 times a day, 1 capsule at a time.
Sponsors
Cheonan Korean Medicine Hospital of Daejeon University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Adults between the ages of 19 and 80 2. In case of persistent respiratory symptoms (cough, sputum) (BCSS score of 1 or higher) 3. FEV1/FVC 70% or more 4. Those who voluntarily agreed in writing to participate in this clinical trial
Exclusion criteria
Exclusion criteria: 1. Persons with any of the following respiratory diseases or a history - Respiratory diseases accompanied by destruction of the underlying lung parenchyma (tuberculosis destroyed lung, bronchiectasis, etc.) - In case of confirmed or suspected inflammatory lesions in the lung parenchyma, such as pneumonia or tuberculosis - In case of being diagnosed and treated for bronchial asthma, COPD, influenza, pneumonia, lung cancer, etc. - Acute bronchitis, chronic bronchitis (BCSS score of 9 or higher and persistent cough and sputum symptoms for at least 3 months per year for 2 consecutive years) 2. If you have uncontrolled cardiovascular disease 3. Those who have taken systemic corticosteroids or immunosuppressants within 4 weeks of their first visit, or who have taken health functional foods or medicines for the purpose of controlling antitussive expectoration 4. Persons with reduced renal function (serum creatinine = 2 mg/dL or on dialysis due to chronic renal failure) 5. Those with decreased liver function (total bilirubin = 2 mg/dL or AST or ALT = 3 times the upper limit of normal) 6. Uncontrolled mental illness, alcoholic 7. Among those who participated in other clinical studies within 1 month of the screening visit, those who received intervention 8. Pregnant or lactating women 9. Persons judged by the researcher as inappropriate to participate in this research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BCSS(Breathlessness, Cough and Sputum Scale);Lung function test FEV/FVC(Forced Expiratory Volume in 1 second / Forced Vital Capacity) | — |
Secondary
| Measure | Time frame |
|---|---|
| Intrabronchial inflammatory marker concentration;CAT score(COPD assessment test) | — |
Countries
Korea, Republic of
Contacts
Public ContactPark chae-hyun
Cheonan Korean Medicine Hospital of Daejeon University
Outcome results
None listed