None listed
Conditions
Sponsors
Seoul National University Bundang Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients 65 years of age or older who are hospitalized or scheduled to be hospitalized due to acute illness. 2. Patients categorized to Frail or Prefrail assessed by Korean version of the Fatigue, Resilience, Ambulation, Illness and Loss of Weight scale (K-FRAIL) 3. Patients having two or more of the following diseases (hypertension, diabetes, ischemic heart disease, chronic lung disease, arthritis, stroke, depression, chronic kidney disease, dementia) 4. Patient who are living at home for more than 3 months before hospitalisation. 5. (For substudy 3 only) Patients who subject to conventional primary chemotherapy because local treatment for curative purposes (such as surgery, concurrent chemoradiotherapy, radiation therapy, etc.) is ineligible (stage stage 3 or higher) 6. (For substudy 3 only) Patients confirmed histologically as cancer (gastric adenocarcinoma, colon adenocarcinoma, non-small cell and small cell lung cancer, pancreatic adenocarcinoma, biliary adenocarcinoma)
Exclusion criteria
Exclusion criteria: 1. Patients who planned hospitalisation in the specialised care unit, such as an intensive care unit and/or acute stroke ward, at the time of admission 2. Patients whose stage is terminal requiring hospice or palliative care. 3. Life expectancy is less than 6 months 4. Serious conditions that limit the participation in the research 5. (For substudy 3 only) Patients who planned to use oral targeted therapy as a palliative first-line chemotherapy 6. (For substudy 3 only)) Patients who recur within 6 months after completion of adjuvant chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| living at home 3 months after discharge | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospital stay;Unplanned re-admission ;All-cause mortality;Overall treatment utility ;Quality of Life;length of days living at home ;Incidence of geriatric syndrome during hospitalization ;Visit to emergency room after disrcharge ;cost-utility analysis;Living at home at 6 months after discharge ;reduce in total number of medications or inappropriate medication;Degree of recognition of advance directive;Changes in sarcopenic obesity;Validation of anticancer drug toxicity prediction model;Readiness for hospital discharge ;therapeutic alliance between patient and provider ;Family interaction ;Empowerment;Frailty;functional status | — |
Countries
Korea, Republic of
Contacts
Public ContactJung-yeon Choi
Seoul National University Bundang Hospital
Outcome results
None listed