Pilot study to determine the extent of resection when C11-Acetate PET guided navigation surgery is performed in patients with brain tumors

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0006269

Enrollment

Registered

2021-06-17

Start date

2020-12-10

Completion date

Unknown

Last updated

2021-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : Previously, MRI navigation surgery used for glioma surgery aimed at resecting all areas with contrast enhancement, whereas Acetate PET/CT navigation surgery in this study aims to r

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adult males and females 20 years of age or older 2. Patients with primary glioma diagnosed for the first time

Exclusion criteria

Exclusion criteria: 1. Patients who received chemotherapy or radiation therapy as a pre-treatment 2. In the case of those who cannot read the consent form (eg, illiterate, foreigner, etc.)

Design outcomes

Primary

Measure	Time frame
Analyze the resected tissue and analyze whether there is a histological difference between the core portion where MRI enhancement and acetate uptake coexist, the portion where there is no MRI enhancement enhancement, only acetate uptake, and the margin of the normal tissue side. Find the most suitable value by cutoff of Acetate PET ROI.	—

Secondary

Measure	Time frame
Overall and Progression Free Survival of Patients Operated by Acetate PET/CT Navigation Surgery	—

Countries

Korea, Republic of

Contacts

Public ContactDongwoo Kim

Yonsei University Health System, Severance Hospital

kdwoo@yuhs.ac+82-2-2228-4855

Outcome results