None listed
Conditions
Interventions
Others : When skin suturing begins, maintain the BIS in a steady state until the end of the surgery as follows.
1. Deep general anesthesia group: BIS 30±5 maintenance
2. Shallow general anesthesia g
Sponsors
Samsung Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patents who have American society of anesthesiologist physical status I to III 2) Patients who are planned to undergo elective major abdominal surgery using propofol-remifentanil anesthesia taking one hour or more.
Exclusion criteria
Exclusion criteria: 1) Pediatric patient at or under 18. 2) Body Mass Index > 35 kg / m 2 or <18.5 kg / m 2 3) Severe liver disease 4) Severe kidney disease (GRF <30 or under hemodialysis) 5) Neuromuscular disease or mental illness 6) Those diagnosed with metabolic diseases 7) Drug addiction or alcohol addiction 8) Emergency surgery 9) Pregnant women or nursing women 10) People who have contraindications to muscle relaxants and sugammadex - Patients who have allergies to drugs or have a history of hypersensitivity reactions, respiratory disease patients, arrhythmia patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical sign of arousal (eye opening, cough, spontaneous movements, response to simple commands, complete recovery) | — |
Secondary
| Measure | Time frame |
|---|---|
| The change in BIS value after the sugammadex administration;The change in BIS-EMG value after the sugammadex administration;awake or recall during the surgery | — |
Countries
Korea, Republic of
Contacts
Public Contactjeayoun kim
Samsung Medical Center
Outcome results
None listed