None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Healthy volunteers who are between the ages of 19 and 45 - Reported current stress and tension symptoms on self-report questionnaire (scoring more than 50% on the Visual Analog Scale, VAS) - Reported mild depressive symptoms during psychiatric interview (scoring between 8~16 on Hamilton Rating Scale for Depression, HAM-D)
Exclusion criteria
Exclusion criteria: - Diagnosed with any axis 1 psychiatric disorders including major depressive disorder (bipolar disorder, alcohol dependence, schizophrenia, etc.) evaluated with a structured clinical interview - Diagnosed with any major medical or neurological disorders assessed during medical history taking, physical examination or experimental tests - History of traumatic brain injury with loss of consciousness or convulsions - Had taken psychotropic drugs within the past 2 months before study participation - Planning for pregnancy during the period of study participation, currently pregnant or breastfeeding - Any contraindications to MRI (i.e., claustrophobia, metallic foreign devices in the body)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the depressive symptom levels assessed by the Beck Depression Inventory (BDI) | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in brain structure assessed by magnetic resonance imaging data;Change in brain metabolism assessed by magnetic resonance imaging data;Change in brain function assessed by magnetic resonance imaging data;Change in brain structural connectivity assessed by magnetic resonance imaging data | — |
Countries
Korea, Republic of
Contacts
Ewha Womens University