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Effects of Transcranial Direct Current Stimulation in Combination with Transcranial Magnetic Stimulation on Stress and Mild Depressive Symptoms

Effects of Transcranial Direct Current Stimulation in Combination with Transcranial Magnetic Stimulation on Stress and Mild Depressive Symptoms

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0006214
Enrollment
160
Registered
2021-06-02
Start date
2021-06-21
Completion date
Unknown
Last updated
2021-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(transcranial direct current stimulation, conventional repetitive transcranial magnetic stimulation, deep repetitive transcranial magnetic stimulation) : [Study 1] After tDCS every day for 2 wee

Sponsors

Ewha Womens University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Healthy volunteers who are between the ages of 19 and 45 - Reported current stress and tension symptoms on self-report questionnaire (scoring more than 50% on the Visual Analog Scale, VAS) - Reported mild depressive symptoms during psychiatric interview (scoring between 8~16 on Hamilton Rating Scale for Depression, HAM-D)

Exclusion criteria

Exclusion criteria: - Diagnosed with any axis 1 psychiatric disorders including major depressive disorder (bipolar disorder, alcohol dependence, schizophrenia, etc.) evaluated with a structured clinical interview - Diagnosed with any major medical or neurological disorders assessed during medical history taking, physical examination or experimental tests - History of traumatic brain injury with loss of consciousness or convulsions - Had taken psychotropic drugs within the past 2 months before study participation - Planning for pregnancy during the period of study participation, currently pregnant or breastfeeding - Any contraindications to MRI (i.e., claustrophobia, metallic foreign devices in the body)

Design outcomes

Primary

MeasureTime frame
Change in the depressive symptom levels assessed by the Beck Depression Inventory (BDI)

Secondary

MeasureTime frame
Change in brain structure assessed by magnetic resonance imaging data;Change in brain metabolism assessed by magnetic resonance imaging data;Change in brain function assessed by magnetic resonance imaging data;Change in brain structural connectivity assessed by magnetic resonance imaging data

Countries

Korea, Republic of

Contacts

Public ContactJungyoon Kim

Ewha Womens University

jungyoon.kimm@gmail.com+82-2-3277-6555

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026