Effect of flumazenil on emergence agitation after orthognathic surgery

Effect of flumazenil on emergence agitation after orthognathic surgery: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0006209

Enrollment

102

Registered

2021-05-28

Start date

2021-05-28

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : At the end of the operation, the anesthetic agent is stopped and flumazenil 0.3mg is administered by IV along with a reversal agent.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 18-65 year-old patients undergoing orthognathic orthognathic surgery under general anesthesia

Exclusion criteria

Exclusion criteria: Pregnant women, under 18 years old, over 65 years old, weight 45 kg or less, 100 kg or more, ASA 3 or more, patients with brain or psychiatric disorders or taking related drugs, patients with severe cardiovascular, kidney, liver, or hematologic abnormalities

Design outcomes

Primary

Measure	Time frame
Frequency of emergence agitation during arousal (AFPS 3 points or higher)	—

Secondary

Measure	Time frame
Time to first reaction from arousal;extubation time;Duration of emerence agitation	—

Countries

Korea, Republic of

Contacts

Public ContactCHONGWHA BAEK

Chung-Ang Univerisity Hospital

nbjhwa@naver.com+82-2-6299-2579

Outcome results