None listed
Conditions
Interventions
Medical Device : For normal, preclinical dementia, mild cognitive impairment, and dementia patients, the near-infrared light emitting part (LED) and the light receiving part (PD) were attached to the
Sponsors
Gwangju Institute of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Criteria for Selecting Research Subjects ? Adult men and women without a physical or mental history other than dementia (over 20 years old-under 100 years old) ? Normal person with no symptoms of dementia (severity level 0) ? Preclinical AD dementia patient (severity stage 1) or Patients with mild cognitive impairment (severe level 2) All subjects were those who performed MMSE, SNSB, PET-CT, MRI, fNIRS olfactory stimulation test, and ApoE gene test within 1 year.
Exclusion criteria
Exclusion criteria: ¦ Criteria for Excluding Research Subjects ? If it is judged that the experiment is impossible because you have not been able to sit still for more than 10 minutes ? In case the stimulus screen or the stimulus sound is not recognized due to insensitivity to sight or hearing ? If you are unable to walk alone due to a severe gait disorder ? When it is judged that walking and balance-related behavior experiments cannot be performed due to a high risk of falling ? Dementia patients with difficult daily life
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Confirmation of the difference in near-infrared signal between the normal group and the preclinical Alzheimer's dementia patient group | — |
Secondary
| Measure | Time frame |
|---|---|
| fNIRS signal amplitude rate for each group;The ratio between fNIRS oxygen hemoglobin and reduced hemoglobin signals in each group | — |
Countries
Korea, Republic of
Contacts
Public ContactJaewon Kim
Gwangju Institute of Science and Technology
Outcome results
None listed