None listed
Conditions
Interventions
Others : Before MRI acquisition, patients give consent for undergoing mpMRI and participating this study. Upon image acquisition, an independent research co-ordinator will prepare two image sets which
no category upgrade from category 3 to category 4 for peripheral zone lesions.
Two interpretation reports by two independent readers will be provided to a biopsy performer who is blind to allocation r
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A. Age = 19 and < 80 years B. Patients referred for prostate multiparametric MRI before a prostate biopsy
Exclusion criteria
Exclusion criteria: - History of androgen deprivation therapy or pelvic radiation therapy - Patients with GFR < 50mls/min - Contraindication to MRI (i.e., cardiac pacemaker or claustrophobia) - History of hip prosthesis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportions of patients who require biopsy (proportions of patients with MRI-positive findings) for identification of suspicious lesions | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare clinically significant prostate cancer (csPCa; defined as Gleason = 7 (3+4) cancer) detection rates detected by mpMRI and fast-bp MRI;To compare clinically insignificant prostate cancer (defined as Gleason = 6) detection rates detected by mpMRI and fast-bp MRI;To compare the number of suspicious lesions on a per-lesion level;The number of positive biopsy cores per total biopsy cores of mpMRI and fast-bpMRI;Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of mpMRI and fast-bpMRI for detection of csPCa on a patient-basis and lesion-basis;Proportion of indeterminate category (PI-RADS category 3) | — |
Countries
Korea, Republic of
Contacts
Public ContactKye Jin Park
Asan Medical Center
Outcome results
None listed