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Comparison of effect of continuous infusion of esmolol alone and in conjunction with ramosetron and administration of ramosetron alone during laparoscopic cholecystectomy on postoperative nausea and vomiting

Comparison of effect of continuous infusion of esmolol alone and in conjunction with ramosetron and administration of ramosetron alone during laparoscopic cholecystectomy on postoperative nausea and vomiting

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0006178
Enrollment
150
Registered
2021-05-25
Start date
2018-02-06
Completion date
Unknown
Last updated
2021-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Group R was administered Ramosetron 1A (ample) at the end of surgery. Group E was intravenously administered a bolus of Esmolol (1.0 mg/kg) before endotracheal intubation and infused Esmolol du

Sponsors

Soon Chun Hyang University Hospital Cheonan
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients with Laparoscopic cholecystectomy on American Society of Anesthesiologist physical status I~II

Exclusion criteria

Exclusion criteria: . Patients who previously experienced the side effects of esmolol or ramosetron, showed hypersensitivity to esmolol or ramosetron, had cardiovascular, lung, or kidney conditions, had neurologic disorders, or were pregnant were excluded.

Design outcomes

Primary

MeasureTime frame
nausea, Retching, Vomiting—

Secondary

MeasureTime frame
Visual analogu scale—

Countries

Korea, Republic of

Contacts

Public ContactJi Young

Soon Chun Hyang University Hospital Cheonan

phmjjy01@hanmail.net+82-41-570-2114

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026