None listed
Conditions
Interventions
Dietary Supplement : Experimental Group - Investigational Product (Silk peptide)
• Ingredient: Silk peptide (Sil-Q1)
• Type: granular stick
• Weight: 3.39g/stick
• Directions: 1 stick, twice a day wit
Sponsors
Yonsei University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Healthy male and female volunteers over 50 years old 2) Screening result for WBC counts in between 3×103 cells/?~8×103 cells/? 3) Volunteers who have received specific experimental illustration and agreed to participate in the study and provided a written content by him/herself
Exclusion criteria
Exclusion criteria: 1) Those received influenza vaccination within 3 months before screening 2) Those with BMI under 18.5 kg/m2 or over 30 kg/m2 3) Those under the treatment for clinically significant acute or chronic diseases in cardiovascular, immune, respiratory, liver, biliary, renal, urinary, nervous, musculoskeletal system as well as infectious, hematologic and neoplastic diseases 4) Those who have consumed medicine or health supplements that can affect immune function within 1 month before screening (See prohibited substances) 5) Those who have been treated with antipsychotics within 3 months before screening 6) Those with or suspected to have alcoholism or substance abuse 7) Those who participated in other researches within 3 months before screening 8) Those with these results in diagnostic medical examination ? blood AST or ALT levels greater than 3 times of upper limit from reference, serum creatinine level greater than 2.0 mg/dl 9) Those who are pregnant or breastfeeding during this study 10) Those who did not accept implementation of the appropriate contraception method among urban elligible women 11) Those who are deemed inappropriate by the researcher
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunoglobulin (IgG1, IgG2);Upper airway infection survey score (occurrence status, symptom score, duration);NK(Natural Killer) cell activity;Immune related indicator (IFN-?, TNF-a, IL-6, IL-1ß, IL-2, IL-12, Adiponectin) | — |
Secondary
| Measure | Time frame |
|---|---|
| Diagnostic medicine inspection (Hematological test, hemochemical test, urine test, pregnancy response test );Vital signs (blood pressure, pulse, body temperature);Survey on meal intake and activity;Adverse reactions;Physical examination/measurement | — |
Countries
Korea, Republic of
Contacts
Public ContactSeungmin Lee
Yonsei University
Outcome results
None listed