The effect of perioperative lidocaine infusion on postoperative level of serum inflammatory cytokines in patients undergoing robot-assisted laparoscopic radical prostatectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0006084

Enrollment

Registered

2021-04-13

Start date

2021-09-13

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : The difference between experimental and conventional groups : lidocaine infusion in experimental group vs. normal saline infusion in conventional group 1) Experimental group Drug name: Lidoca

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1) Adult 2) elective robot-assisted laparoscopic radical prostatectomy 3) American Society of Anesthesiologists (ASA) physical status I or II

Exclusion criteria

Exclusion criteria: 1) refusal to participate in the study 2) decision-making vulnerable being 3) history of drug side effects - allergy, arrhythmia, severe hypotension (mean blood pressure <60 mmHg), severe bradycardia (<40beats/min) 4) Hemorrhage that urgently required packed red blood cells - hemoglobin <7 g/dL 5) History of vascular disease 6) History of pulmonary disease 7) History of cardiac disease

Design outcomes

Primary

Measure	Time frame
measurement of serum cytokines (interleukin-6, interleukin-10, interleukin-17, tumor necrosis factor-alpha, ??? interferon-gamma)	—

Secondary

Measure	Time frame
Biochemical recurrence of prostate cancer;Clinical patient recovery - pain, length of stay, Clavien-Dido classification;Experimental drug-related complications	—

Countries

Korea, Republic of

Contacts

Public ContactJung-Woo Shim

The Catholic University of Korea, Seoul St. Mary's Hospital

tintinshim@gmail.com+82-2-2258-6150

Outcome results