None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Subjects between 19 and 89 years old adult male and female who has more than or equal to 20 teeth.
Exclusion criteria
Exclusion criteria: ? Patients who received periodontal treatment within last 4 months. ? History of antibiotic use within last 3 months. ? History of immunosuppressant or corticosteroids within last 3 months. ? Patients who has less than 20 teeth. ? Patients with uncontrolled diabetes or hypertension. ? Patients with severe cardiovascular disease, respiratory disease, kidney disease, liver disease, GI tract disease, blood disorders or neuropsychiatric disorders. ? Patients with hyperthyroidism or hypothyroidism. ? Pregnant women. ? Patients with autoimmune disease. ? History or present with malignant cancer in jaw. ? History or present with drug or alcohol abuse within last 1 year. ? Patients with other inflammatory disease such as stomatitis, oral cancer in addition to periodontal disease. ? In cases where the researcher determines that participation is inappropriate due to ethical or unwanted impact on the results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of expression of biomarkers | — |
Secondary
| Measure | Time frame |
|---|---|
| Amount of oral microorganisms | — |
Countries
Korea, Republic of
Contacts
Seoul National University Dental Hospital