Clinical Impact of Blood Pressure Control on Clinical Outcome in Atrial fibrillation Patients with Hypertension

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0006055

Enrollment

250

Registered

2021-04-05

Start date

2021-05-03

Completion date

Unknown

Last updated

2021-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : -Intensive BP treatment: Antihypertensive drug (renin-angiotensin system blocker + calcium channel antagonist + long-acting time diuretic (chlorthalidone) combined therapy with the single-pill

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ? Patients aged 19 or older with non-membrane atrial fibrillation ? Patients with hypertension who need medication *Patients with hypertension who require drug treatment currently follow the guidelines for hypertension treatment of the Korean Society of Hypertension in 2018. ? Patients who have not previously taken antihypertensive drugs ? Patients who agree with the purpose of this study

Exclusion criteria

Exclusion criteria: ? Atrial fibrillation accompanied by severe heart malformation or structural heart disease affected by hemodynamics ? Severe renal dysfunction ? Patients with a history of atrial fibrillation high frequency electrode catheter resection or labyrinth surgery ? Patients with significant mitral valve stenosis (moderate or higher) ? Patients with active internal bleeding ? Patients diagnosed with hypertrophic cardiomyopathy ? Polycystic kidney disease ? Significant comorbid disease ? Patients whose survival period is expected to be less than 1 year ? Patients with drug or alcohol addiction ? Patients diagnosed with stroke within the last 3 months ? Patients judged unsuitable for participation in clinical trials by the judgment of other researchers

Design outcomes

Primary

Measure	Time frame
After the normal sinus rhythm, the patient included in the RCT was analyzed using the retention rate and intention to treat analysis.Including interim analysis of patients who followed up for more than 30 days using per-protocol analysis.	—

Secondary

Measure	Time frame
-Blood pressure control (average of self-monitoring blood pressure, average of 24-hour active blood pressure monitoring)-Assessment of the incidence of cerebral infarction, hospitalization, cardiovascular events, mortality, and quality of life (SF-36)	—

Countries

Korea, Republic of

Contacts

Public ContactKim Jeong

Inha University Hospital

yoojeong1227@naver.com+82-32-890-2555

Outcome results