None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: patients with MCI met Peterson’s criteria of (1) memory complaint, corroborated by an informant, (2) objective memory impairment for age, level of education, and sex; (3) essentially preserved general cognitive function; (4) mostly intact functional activities; and (5) no dementia. All patients with MCI had an overall Clinical Dementia Rating of 0.5. Objective memory impairment was defined as a performance score of 1.5 standard deviations (SDs) below the respective age-, education-, and sex-specific normative means on at least one of the four episodic memory tests included in the CERAD-K, that is, WLM, WLR, WLRc, and CR.
Exclusion criteria
Exclusion criteria: We excluded participants with any history of alcoholism, drug abuse, head trauma, or psychiatric disorders, those taking any psychotropic medications (e.g., cholinesterase inhibitors, antidepressants, benzodiazepines, and antipsychotics), those with multiple vascular risk factors, and those with extensive cerebrovascular disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive function scores;parameters values of brain magnetic resonance imaging | — |
Secondary
| Measure | Time frame |
|---|---|
| cognitive function subdomains scores;functional segregation and integration parameters of brain magnetic resonance imaging | — |
Countries
Korea, Republic of
Contacts
The Catholic University of Korea, Yeouido St. Mary's Hospital