None listed
Conditions
Interventions
Drug : intervention(CSBHT) and control (placebo), 1 pack 3 times a day for 8 weeks, 1 hr after meal
Sponsors
Kyung Hee University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) male and female aged 19-85 2) patients who have been diagnosed with asthma and treated for more than 4 weeks 3) patients who are administered ICS/LABA and montelukast or ICS and montelukast 4) patients who voluntarily decide to participate in this clinical trial and signs a consent form
Exclusion criteria
Exclusion criteria: 1) Patients with serious abnormalities such as pneumonia, interstitial lung disease, and active pulmonary tuberculosis on chest X-ray examination 2) Patients who have been using maintenance therapy with oral steroids since 4 weeks ago, are receiving anti-IgE antibodies, or taking herbal medicines for asthma treatment. 3) more than AST/ALT twice the normal value or Cr 1.5 mg/dL. 4) chronic heart failure of class III or IV (New York Heart Association) 5) Patients with alcohol or other substance abuse/dependency or history 6) Patients with malignant tumors or a history of malignant tumors (however, if they have not recurred for more than 5 years, participation is possible) 7) Patients with a history of hypersensitivity reactions or allergies to research-related drugs 8) Patients who are unable to read and write or have cognitive impairment 9) Pregnant or lactating women 10) patients who participated in other clinical trials within recent 30 days prior to this clinical trial (based on the date of written consent) 11) If the researcher determines that it is inappropriate for participation in clinical research due to other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of FEV1(forced expiratory volume in one second) | — |
Secondary
| Measure | Time frame |
|---|---|
| change of peak expiratory flow rate (PEFR);change of bronchoprovocation test and Fractional Exhaled Nitric Oxide (FeNO);change of St. George’s Respiratory Questionnaire (SGQR) and Asthma Control Test (ACT);frequency of rescue medicine;questionnaire of asthma symptoms of korean medicine;Serum IgE, eosinophil count, CRP | — |
Countries
Korea, Republic of
Contacts
Public ContactBeom-Joon Lee
Kyung Hee University Hospital
Outcome results
None listed