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Effect of intravenous dexamethasone on analgesic duration of interscalene brachial plexus block for arthroscopic shoulder surgery

Effect of intravenous dexamethasone on analgesic duration of interscalene brachial plexus block for arthroscopic shoulder surgery: a randomized non-inferiority trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0005998
Enrollment
84
Registered
2021-03-15
Start date
2021-03-17
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : The participants were randomly assigned to two groups: low-dose local anesthetic-dexamethasone intravenous infusion and high-dose local anesthetic-dexamethasone non-use. Depending on the group

Sponsors

Seoul National University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients aged 19 to 80 years undergoing shoulder arthroscopic surgery for a rotator cuff tear under general anesthesia, within ASA class I-III

Exclusion criteria

Exclusion criteria: ? Patients who refused to participate in the study ? Patients who cannot maintain their own patient-controlled analgesia (PCA) ? Patients with respiratory diseases such as asthma and chronic obstructive pulmonary disease ? Patients with neurological abnormalities of the upper limb ? Patients with a history of surgery around the neck on the ipsilateral side of the surgery site, and radiation therapy ? Patients who are regularly using steroid drugs ? Pregnant women ? Patients with a history of allergy or hypersensitivity to local anesthetics and dexamethasone ? Patients who are contraindicated to take dexamethasone

Design outcomes

Primary

MeasureTime frame
The duration of the analgesic effect (The time from the completion of the brachial plexus block to when the patient first feels pain of NRS 4 or higher);Incidence of diaphragmatic palsy

Secondary

MeasureTime frame
Pulmonary function test results before and after surgery;NRS scores checked at 4 hour intervals after surgery;Time from completion of brachial plexus block until the first demand for analgesics;Total amount of analgesics used for 24 hours postoperatively;Overall satisfaction with pain control;Blood glucose levels measured in 6AM at the day after surgery;Nausea and vomiting within 24 hours after surgery

Countries

Korea, Republic of

Contacts

Public ContactYoungwon Kim

Seoul National University Hospital

youngwon.md@gmail.com+82-2-2072-3283

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 6, 2026