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Effect of donepezil on the onset and duration time of neuromuscular blocking agent

Effect of donepezil on the onset and duration time of neuromuscular blocking agent

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0005979
Enrollment
60
Registered
2021-03-09
Start date
2021-03-08
Completion date
Unknown
Last updated
2021-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Chonnam National University Hospital Hwasun Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Patients scheduled to undergo elective surgery under general anesthesia at Hwasun Chonnam National University Hospital; - Patients taking Donnefezil due to dementia (Patient group) - Patients with no history of taking Donnepzil (control group)

Exclusion criteria

Exclusion criteria: -Paitents with history of drug and other hypersensitivity reactions -Patients with significant neuromuscular disease or problems -Patients with significant renal or liver disease -Patients who require rapid sequence induction -Patients taking medication with potential to affect the neuromuscular transmission system; -Other patients deemed inappropriate by the researcher

Design outcomes

Primary

MeasureTime frame
Time from injetion of rocuronium to zero TOF count—

Secondary

MeasureTime frame
Time from injetion of rocuronium to one TOF count (for 3 consecutive times);Time from injetion of rocuronium to four TOF count (for 3 consecutive times)—

Countries

Korea, Republic of

Contacts

Public ContactSeongheon Lee

Chonnam National University Hospital Hwasun Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026