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A study on thyroid cancer, detecting circulating tumor cells and BRAF gene mutations through preoperative blood tests, and comparing the identified BRAF gene mutations to postoperative pathological tissue BRAF gene mutations

A study on thyroid cancer, detecting circulating tumor cells and BRAF gene mutations through preoperative blood tests, and comparing the identified BRAF gene mutations to postoperative pathological tissue BRAF gene mutations

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0005820
Enrollment
20
Registered
2021-01-25
Start date
2021-02-01
Completion date
Unknown
Last updated
2021-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Seoul National University Bundang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients over 20 years of age Patients who agree to the study and undergo thyroidectomy for thyroid cancer

Exclusion criteria

Exclusion criteria: Patients with diseases other than the thyroid gland Patients who cannot communicate Patients who refused the study Patients with non-thyroid papillary cancer on postoperative biopsy

Design outcomes

Primary

MeasureTime frame
The BRAF mutation observed in circulatory tumor cells was compared with the final pathological tissue BRAF mutation. About 70-80% of BRAF mutations were observed in the final pathologic examination of thyroid cancer in Korean patients. At this time, it was confirmed that the BRAF mutation of circulating tumor cells was also observed in 70-80%. In addition, it was confirmed that BRAF mutations were observed simultaneously in each

Secondary

MeasureTime frame
The relevance of thyroid cancer by stage. In general, BRAF mutations are observed as the stage of thyroid cancer increases. In other words, we want to confirm whether there is a relationship between the BRAF mutation in circulatory tumor cells and the stage of thyroid cancer.

Countries

Korea, Republic of

Contacts

Public ContactHyeong Won Yu

Seoul National University Bundang Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026