None listed
Conditions
Interventions
Medical Device : The goal of the proposed study is to investigate the modulation of stroke induced abnormal intermuscular coordination of upper extremity and its effect on the motor function after the
the training time per block and the number of block can be adjusted)
Sponsors
Korea Advanced Institute of Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Late subacute or chronic stroke (=3 months post-onset) (2) unilateral ischemic or hemorrhagic stroke (3) hemi-paresis
Exclusion criteria
Exclusion criteria: (1) Neurological disorder other than stroke (2) Receiving botulinum toxin on the impaired arm within 3 months (3) Cognitive dysfunction that precludes comprehension of experimental tasks and the provision of written informed consent (score lower than 18 on the Korean version of Mini-Mental Status Examination) (4) Severe spasticity (Modified Ashworth <4) (5) Sign of severe concurrent medical problems (including shoulder pain) sufficient to preclude repetitive reaching to targets (verbally asked during pre-screening)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle synergy (composition and activation of muscle synergies);Brain activity and functional connectivity of regions of interest;End-point force (direction, magnitude, and moment in 3D force space);Level of upper limb motor impairment (Fugl-Meyer Assessment);Upper limb motor function (Wolf Motor Function Test) | — |
Secondary
| Measure | Time frame |
|---|---|
| Upper limb joint motion (3D translation of glenohumeral joint center, 3 DOF rotation of shoulder and 1 DOF rotation of elbow | — |
Countries
Korea, Republic of
Contacts
Public ContactHyeok-Jun Kwon
Korea Advanced Institute of Science and Technology
Outcome results
None listed