None listed
Conditions
Interventions
None listed
Sponsors
Yonsei University Yongin Severance Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 1) Patient group: the patients with aortic valve sclerosis as proven by thransthoracic echocardiography 2) Control group: the subjects without aortic valve sclerosis and with age &sex-matched to patients group 2. Consent for using human biological material in research 3. Consent for using clinical and medical records for research
Exclusion criteria
Exclusion criteria: 1. Bone marrow disease including hematologic malignancy 2. Subjects who have not extracted enough amount of DNA for NGS panel analysis 3. Over than mild aortic valve stenosis 4. Subjects who does not understand the purpose and method of clinical trials due to over than a moderate severity of dementia, mental illness, or neurological disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the difference in CHIP positive rate between the patients with aortic valve sclerosis and control groups | — |
Secondary
| Measure | Time frame |
|---|---|
| the difference in CHIP positive rate according to severity of aortic valve sclerosis between the patients with aortic valve sclerosis and control groups, proportion of each component of CHIP in patients with aortic valve sclerosis | — |
Countries
Korea, Republic of
Contacts
Public ContactMinkwan Kim
Yonsei University Yongin Severance Hospital
Outcome results
None listed