FindTrial
Sign In

The clinical effect of Sacubitril / Valsartan in patients with heart failure

A multicenter retrospective registry to perform the REal world efficacy of Clinical Outcome and adverse left ventricular Remodeling in patients with heart failure with reDuced ejection fraction treated with Sacubitril/Valsartan (RECORD-SV)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0005747
Enrollment
200
Registered
2021-01-08
Start date
2020-12-17
Completion date
Unknown
Last updated
2021-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Soon Chun Hyang University Hospital Bucheon
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) All patients aged 18 years of age or older with reduced LV systolic function (LVEF=40%) are targeted 2) Patients who are taking Sacubitril/valsartan or who are taking conventional ACEi/ARB oral medications and have been replaced with Sacubitril/valsartan.

Exclusion criteria

Exclusion criteria: 1) Severe shock or hypotension at registration 2) Those who have a history of angioedema 3) Those who have hypersensitivity reactions and side effects to ACE inhibitors, ARB, and NEP inhibitors 4) Patients who are pregnant or may become pregnant 5) Patients with cancer history within 5 years

Design outcomes

Primary

MeasureTime frame
The degree of change of left ventricular end systolic volume on echocardiography—

Secondary

MeasureTime frame
Composite endpoints of death, non-fatal myocardial infarction, and hospitalization for stroke and heart failure;Cardiovascular death;Myocardial infarction;Stroke;Hospitalization for heart failure;Visit ER for symptoms of heart failure;Revascularization for ischemia;Echocardiographic parameter;Microalbuminuria;NT-pro BNP;BMI, Body weight—

Countries

Korea, Republic of

Contacts

Public ContactInki Moon

Soon Chun Hyang University Hospital Bucheon

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026