None listed
Conditions
Interventions
Dietary Supplement : Experimental material (BRB&PG-F): 2 times per day, 2 tablets per dose, at morning and evening (total compound, 600 mg/day)
Sponsors
Ajou University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Those who agreed to participate in this trial and presented a document, voluntarily signed by the subject and the parent (or legal representative) 2) Those who aged 3 to 15 years 3) Those who have persistent atopic dermatitis symptoms for more than 6 months 4) Those who have SCORAD scores between 25 and 50 (moderate) at the time of screening and randomization
Exclusion criteria
Exclusion criteria: 1) Those who have skin disease other than atopic dermatitis, which impairs accurate evaluation of atopic dermatitis results such as irritant contact dermatitis, allergic contact dermatitis, infection (e.g., ohms) or psoriasis 2) Those who have skin or dermatitis (bacteria, viruses, fungi) that require full body treatment within 2 weeks of screening (except for localized water lions with fewer than 20 lesions and viral warts) 3) Those who have systemic diseases such as immune deficiencies, autoimmune diseases, cancer, etc. 4) Those who administered the following medicines or received the following treatment before screening A. Those who administered systemic antibiotics, corticosteroids and immunosuppressants within 2 weeks of screening B. Those who took herbal medicine, health function foods in relation to atopic dermatitis within 4 weeks of screening are {Demonne products (VSL#3) and lactobacillus products licensed for atopic dermatitis (Sake Probio65, Lactobacillus plantarum CJLP133, L. Rhamnosus IDCC3201)} C. Those who received phototherapy within 4 weeks of screening D. Those who administered local steroids, antihistamines, local immuno-suppressants, oral antihistamines or local antibiotics within a week of screening 5) Those who have infectious bowel disease history within 2 weeks of screening 6) Those who have an overreaction history in the ingredients of food for human application testing (e.g. mushrooms, balloon flower root, black rice and milk) 7) Those who participated in other clinical trials within 2 months of the start of this clinical trial (including a human application test) or have a plan to participate in another interventional clinical trial (including a human application trial) after the start of this human application trial 8) Those who considered as inappropriate for this clinical trial by the judgment of the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SCORAD total score at week 12;SCORAD total score at week 6 | — |
Secondary
| Measure | Time frame |
|---|---|
| Cytokines and immunological markers | — |
Countries
Korea, Republic of
Contacts
Public ContactJihyun Moon
Ajou University Hospital
Outcome results
None listed