The Efficacy of Low-Intensity Pulsed Ultrasound through Articular Cartilage and Clinical Evaluations in Patients with Knee Osteoarthritis: a prospective single-arm clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0005506

Enrollment

Registered

2020-10-20

Start date

2019-04-11

Completion date

Unknown

Last updated

2021-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : Ultrasound stimulation time: 30 minutes/1 day Ultrasound stimulation period: 1 time/day, 5 days/week or more, 4 weeks total 20 times or more Ultrasonic stimulation spot: painful knee

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Men and women over 19 years of age with knee pain 2) Persons diagnosed with Kellgren-Lawrence (K-L) scale on an anterior-posterior plane radiograph of the knee joint in a standing position 3) Those who fully understand the research purpose and procedure and wish to participate in clinical research through voluntary consent

Exclusion criteria

Exclusion criteria: 1) Those who do not meet the age criteria 2) Those who cannot accurately express the pain area and degree due to cognitive decline 3) Persons suspected of neurological disease during physical examination 4) Those who complain of decreased senses 5) Those who have had knee surgery within the last 6 months 6) Those who received lower extremity surgery and cortisone injection treatment within the last 1 month (Steroids, nonsteroidal, anti-inflammatory drugs, etc. are not restricted.) 7) Knee infection, inflammatory joint disease, acute injury to the ligaments and tendons of the knee 8) Those who have symptoms of nerve root compression in the spine, central nervous system disease, polyneuropathy, etc. 9) Pregnant and lactating women, those who responded positive pregnancy by urine test, and those who were expected to become pregnant during the clinical trial 10) Those who do not meet the standard of treatment 11) Persons who are deemed unsuitable for participation by other research directors

Design outcomes

Primary

Measure	Time frame
Visual Analog Scale	—

Secondary

Measure	Time frame
Cartilage regeneration evaluation (articular cartilage thickness before and after treatment on knee MRI);Arthritis Function Score (WOMAC Score);Quality of Life Assessment (SF-36)	—

Countries

Korea, Republic of

Contacts

Public ContactSeung-Rok Kang

Jeonbuk National University Hospital

Outcome results