None listed
Conditions
Interventions
Medical Device, Procedure/Surgery : The purpose of this study is a randomized, controlled, multicenter clinical trial to compare the volume stability of augmented residual alveolar bone after tooth ex
Sponsors
Yonsei University Health System, Dental Hospital
Kyung Hee University Dental Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Selection criteria -Adult men and women who are 18 years of age or older with periodontal health -Central incisors, lateral incisors, canines, 1st and 2nd in maxilla or mandible due to severe periodontal disease Patients requiring extraction during premolar -Patients who are expected to observe vertical resorption of at least one of the buccal and lingual bone wall with the tooth extraction after extraction is equivalent to 1/2 or more of the root length of the tooth -Those who can comply with research procedures -Those with a signed consent form
Exclusion criteria
Exclusion criteria: 2) Exclusion criteria Those who fall under any of the following -Vertical absorption of the buccal bone wall or lingual bone wall from the tooth after extraction is the root of the tooth Patients expected to be observed by a height less than half the length -Bone wall that requires extraction due to severe periodontal disease, but shows severe vertical absorption Patients whose mesial or distal side is not buccal or lingual -Patients with periodontal disease that is not controlled throughout the oral cavity -Patients with metabolic diseases such as uncontrolled diabetes -Patients with a history of receiving radiation therapy and chemotherapy in the head and neck area -Patients with a history of taking drugs that inhibit bone metabolism (Biosphosphonate or Denosumab series) within 4 months -Pregnant women and lactating patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alveolar volume change measured by superimposing intraoral scan images before and after alveolar preservation, and changes in width and height of ridge measured by superimposing CT images immediately after and 6 months after alveolar preservation | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in keratinized gingivals before and after alveolar preservation, measured from intraoral scan images;Evaluation of the need for additional surgery (maxillary sinus transplantation, bone-guided regeneration around implants, etc.) for implant placement through CT images after 6 months of alveolar preservation;Clinical evaluation of bone quality (D1, 2, 3, 4) and bone mass (A, B, C, D) during implant placement;Histological evaluation of new bone formation through analysis of tissue specimens obtained from the area where alveolar preservation was performed;Evaluation of soft tissue healing after alveolar preservation and implant surgery (wound healing index);Survey evaluation of patient satisfaction with alveolar conservative surgery and implant surgery;Evaluate operator convenience through survey content and time required for surgery;Esthetic evaluation after completion of implant prosthesis (pink and white esthetic scores: PES and WES);Marginal bone resorption around placement using apical radiograph;Implant success rate and survival rate | — |
Countries
Korea, Republic of
Contacts
Public ContactJoo Yeon Lee
Yonsei University Health System, Dental Hospital
Outcome results
None listed