Effects of Pursed Lip Breathing on Muscle Oxygenation During walking with a portable oxygen concentrator in Interstitial Lung Disease

Effects of Pursed Lip Breathing on Muscle Oxygenation During walking with a portable oxygen concentrator in Interstitial Lung Disease : A randomized crossover trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0005440

Enrollment

Registered

2020-09-25

Start date

2020-11-30

Completion date

Unknown

Last updated

2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Behavioral : On the first visit, we will obtain consent and screen for research selection criteria. Subjects perform two 6-minute walk tests (30-minute rest) to check for hypoxia during exercise witho

maximum intensity) by applying natural breathing or constricted lip breathing. After that, take a 30-minute break and perform a 6-minute walk test with the second breathing method by crossover assignm

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Interstitial Lung disease patients who diagnosed by forced vital capacity (FVC) <80 % or diffusion capacity (DLCO)<80 %, Adult men and women over 20 years old

Exclusion criteria

Exclusion criteria: 1. Subjects with severe hypoxia (less than 88% of SpO2) at rest 2. Subjects who are limited in 6-minute gait test due to musculoskeletal problems of legs or feet 3. Subjects with limited activity due to heart disease (heart failure NYHA II~IV) 4. Subjects with pain while walking due to arteriovenous vascular disease 5. Subjects who do not understand the test due to cognitive decline 6. Subjects with obesity whose fat thickness of the quadriceps muscle exceeds 1cm 7. Subjects with muscle disease (myositis, myopathy) 8. Pregnant women

Design outcomes

Primary

Measure	Time frame
SmO2% change during exercise (SmO2rest-SmO2nadir)	—

Secondary

Measure	Time frame
6-minute walk distance (6MWD);NIRS (deoxy-hemoglobin, deoxy-myoglobin(HHb rest), HHb(peak), oxy-hemoglobin, oxy-myoglobin (HbO2, rest), HbO2(peak), total hemoglobin, myoglobin (THb = HHb+HbO2), Hb difference (Hbdiff = HbO2-HHb);Pulmonary function test (FEV1, FVC, FEV1/FVC);SpO2% change during exercise (SmO2rest-SmO2nadir)	—

Countries

Korea, Republic of

Contacts

Public ContactCho Hui HONG

Pusan National University Hospital

hch8163@gmail.com+82-51-240-7485

Outcome results