Nutritional Improvement and Mechanism of Liver Cancer Treatment Using Edible Insects

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CRIS

Registry ID

KCT0005437

Enrollment

Registered

2020-09-25

Start date

2020-12-08

Completion date

Unknown

Last updated

2021-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : pill using mealworms, 5g X 6 (30g) / day, 8 weeks of anti-cancer treatment, intake with a plenty of water

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) a patient between ages of 18 and 85 2) Patients schelduled for surgery with pancreatobiliary disease and liver cancer (HCC, CCC, and metastatic liver cancer) 3) Karnofsky Performance status = 70 4) Patients who provide informed consent

Exclusion criteria

Exclusion criteria: Exclusions for patients with any of the following creteria 1) Patients who underwent palliative surgery 2) Patients with uncontrolled preoperative conditions 3) Previous history of surgery affecting nutritional status (ex, gastrectomy, colectomy, etc) 4) Pregnant and lactating women 5) Patients with an allergy to mealworms 6) Patients with a hematological abnormalty - Total bilirubin > 1.5 X upper normal limit - ALT, AST > 2.5 X upper normal limit - ALP > 2.5 X upper normal limit

Design outcomes

Primary

Measure	Time frame
Nutritional marker (phase angle, muscle mass, fat free mass, fat mass, body cell mass)	—

Secondary

Measure	Time frame
Hematologic test (Hemoglobin, Hematocrit, Platelet, WBC, Neutrophil ?);Biochemical test (Total protein, Albumin, Glucose, BUN, Creatinin, Total bilirubin, AST, ALT)	—

Countries

Korea, Republic of

Contacts

Public ContactSeung Eun Oh

Yonsei University Health System, Gangnam Severance Hospital

Outcome results