None listed
Conditions
Interventions
Procedure/Surgery : Acupuncture treatment is performed based on the revised Standards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) 2010 recommendations. Acupuncture treatmen
Dongbang Acupuncture Inc., Bundang, Seongnam, Korea) will be used for acupuncture treatment. The needle will be inserted 5 to 30 mm, depending on the acupoints, and will remain in place for 15 minutes
Sponsors
Kyung Hee University Oriental Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy Group A) Men and Women aged 19 to 49 years old, able to read and write the Korean language 2) Body Mass Index (BMI) 18.5 or more and less than 25 (kg/m2) 3) Right-handed 4) Do not have atopic dermatitis based on Hanifin & Rajka criteria 5) Those with normal or normailly corrected visual acuity. 6) Agreement with a study protocol, and willingness to sign written informed consent 2. Atopic Dermatitis Patient Group 1) Men and Women aged 19 to 49 years old, able to read and write the Korean language 2) Body Mass Index (BMI) 18.5 or more and less than 25 (kg/m2) 3) Right-handed 4) Atopic dermatitis diagnosed according to the Hanifin and Rajka criteria 5) Scores from 10 to 40 points on the objective Scoring Atopic Dermatitis (SCORAD) scale. 6) Those with normal or normailly corrected visual acuity. 7) Agreement with a study protocol, and willingness to sign written informed consent 8) No participation in other clinical studies for the preceding month
Exclusion criteria
Exclusion criteria: 1) Those who have taken drugs such as p.o. antibiotics within the last 1 month, and this drug may affect the test results. 2) Those who have taken health functional foods such as probiotics within the last 1 month, and this health functional food may affect the test results. 3) Those who have a history of drinking within the last week 4) Those with extensive tattoos or (semi) permanent makeup on their face 5) Those with claustrophobia 6) Those who cannot lie down for a certain amount of time due to pain and discomfort 7) Persons with non-removable metals such as: -Pacemaker (Pacemaker) -Artificial heart valve -Cerebral aneurysm clip -Angioplasty (Stent insertion) -Artificial cochlea surgery -Metallic foreign body or acupuncture remaining in the body -Surgical Metal such as artificial joints -Various infusion pumps such as insulin pumps -Hearing aids -Various electrodes attached to the body (Electrodes) -Neural stimulator and various implants (cochlear implant, etc.) -Gold needle -Piercings or other metal decorations that cannot be removed 8) (For women) Pregnancy or breastfeeding 9) (For women) Those with intrauterine contraceptives 10) Those who have had eye surgery (excluding LASIK and LASEK) 11) Those who sufferring from other diseases (neuropsychiatric disorders, brain surgery history, stroke, epilepsy, dementia, alcohol or drug addiction, etc.) that may affect the research results. 12) Those with somatosensory-related diseases (Reynoid's disease, chronic pain disease, etc.) 13) Smokers 14) Those judged that participation in this clinical trial is not appropriate physically and mentally 15) Those who are participating in other clinical trials that may have the potential to affect this clinical trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scoring Atopic Dermatitis(SCORAD) index | — |
Secondary
| Measure | Time frame |
|---|---|
| fMRI image (Changes in the intensity of blood-oxygen-level-dependent signals in thalamus, insula, and anterior cingulate cortex and functional connectivity between this three areas) ;Gut microbiome;EASI, Eczema Area and Severity Index;DLQI, Dermatology life quality index;Abdominal tenderness measurement (Epigastrium,CV12, ST25);GSRS, Gastrointestinal Symptom Rating Scale;TDS, Total Dyspepsia Symptom Scale;Bristol stool scale;AR, Adequate Relief of functional dyspepsia pain and discomfort;Serum TARC (Thymus and Activation-Regulated Chemokine), ATX (Autotaxin) through blood sample collection | — |
Countries
Korea, Republic of
Contacts
Public ContactJundong Kim
Kyung Hee University Oriental Medical Center
Outcome results
None listed