None listed
Conditions
Interventions
Drug : For the probiotic group only In the probiotic group, a
probiotic named Medilac®-DS enteric-coated capsules (Hanmi Pharma Inc., South
Korea), which contain a total of one billion live B. subti
Sponsors
The Forces Medical Command
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: The diagnosis of pneumonia was based on the ATS/IDSA guidelines for community-acquired pneumonia. Patient admitted for more than 48 hours, with no alternative foci of infection identified, plus at least, two of the following criteria - Fever (38?) - Leukocytosis (>12,000/µl) or leukopenia (<4,000/µl) - Purulent respiratory secretions - Rale (or crackle) on physical examination - Abnormal blood gas analysis result Plus, new infiltrates on chest x-ray
Exclusion criteria
Exclusion criteria: - HIV infection, syphylis, diabetes, hypertension, steroid user - Persons with other serious accompanying diseases when judged by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical symptoms (fever, chills, cough, coryza, sputum, diarrhea, constipation), fever subsidence, WBC, Hb, PLT, PT, CRP, AST, ALT, bilirubin, albumin, creatinine, Bristol stool scale;clinical symptoms (fever, chills, cough, coryza, sputum, diarrhea, constipation), fever subsidence, WBC, Hb, PLT, PT, CRP, AST, ALT, bilirubin, albumin, creatinine, Bristol stool scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Distribution of immune cells (regulatory T cells, Th17 cells);Distribution of immune cells (regulatory T cells, Th17 cells) | — |
Countries
Korea, Republic of
Contacts
Public ContactChang Hun Lee
The Forces Medical Command
Outcome results
None listed