Efficacy potential of dietary CJLP55 Lactobacillus strains for anti-sebum and clinical improvement of acne vulgaris

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0005401

Enrollment

Registered

2020-09-22

Start date

2015-07-03

Completion date

Unknown

Last updated

2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : 1. Experimental drug (CJLP55) 1) Main ingredients: Lactobacillus plantarum CJLP55 9% (10^10 CFU), maltodextrin 45.5% and glucose 45.5% 2) Dosage: 2g/day 3) Instruction: Take 1 p

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - The diagnosis for excess sebum on the face (defined as > 150 µg/cm2 on the forehead) was based on the criteria scale of sebum content for oily skin by SM815 sebumeter (Courage + Khazaka Electronic GmbH, Cologne, 1986). - Acne IGA grade ranged from 2 to less than 4 on the face (mild to moderate acnes)

Exclusion criteria

Exclusion criteria: - Acne treatment of any kind including artificial ultraviolet (UV) therapy in the previous 2 months - Other skin disease or systemic illnesses - Use of medication that could interfere with acne at any stage of enrollment in the study.

Design outcomes

Primary

Measure	Time frame
Acne grade;Inflammatory lesion count (ILC);Total lesion count (TLC)	—

Secondary

Measure	Time frame
Sebum, skin hydration and skin pH;Cholesterol, triacylglycerol and free fatty acid;Urine bacterial extracellular vesicles (EV);blood cyotkine levels	—

Countries

Korea, Republic of

Contacts

Public ContactMi-Ju Kim

Kyung Hee University

Outcome results