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Research between gut microbiome and probiotics in coronary artery disease

Research between gut microbiome and probiotics in coronary artery disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0005393
Enrollment
230
Registered
2020-09-09
Start date
2020-09-15
Completion date
Unknown
Last updated
2020-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Kyung Hee University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Target patients: Patients who underwent coronary angiography with chest pain (2) Selection criteria 1) Adults over 19 2) A person who can understand the purpose and contents of this study and voluntarily consent after being fully explained. 3) Cardiovascular disease and control group i. Cardiovascular disease ? Patients who underwent coronary intervention for more than 70% of stenosis in one or more coronary arteries ? Patients with myocardial infarction ? Patients with left ventricular dysfunction (LVEF<45%) ii. Control group: normal coronary artery and normal heart function

Exclusion criteria

Exclusion criteria: 1) Those who do not have voluntary consent, such as cognitive impairment and vulnerable subjects 2) Women of childbearing age or pregnant women 3) Patients suspected of active infection 4) Those who are using systemic antibiotics or receiving immunosuppressive treatment 5) People who have allergies or side effects to intestinal lactic acid bacteria 6) Hemodynamically unstable myocardial infarction patient 7) Uncontrolled hypertension (180/110 mmHg), arrhythmia patients 8) Patients with liver failure and kidney failure

Design outcomes

Primary

MeasureTime frame
Relative proportion of specific bacteria in extracellular vesicles

Countries

Korea, Republic of

Contacts

Public ContactSoHyun Jeong

Kyung Hee University Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026