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Production of SARS-CoV-2 antigen specific immune cell therapy

Production of SARS-CoV-2 antigen specific cytotoxic T lymphocytes

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0005370
Enrollment
10
Registered
2020-09-02
Start date
2020-07-21
Completion date
Unknown
Last updated
2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Biological/Vaccine, Non-Stem Cell : Blood collection of 50cc, once Periphieral blood mononuclear cells are isolated and the cells are expanded in culture using cytokines for 21 days to generate anti

Sponsors

The Catholic University of Korea, Seoul St. Mary's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: For COVID-19 treated individuals: 1. Those who consent to the study 2. Aged 20 - to 65 years old 3. Individual who has been diagnosed with COVID-19 and released from quarantine, that is, the person who meets all the criteria for public release by the CDC: A. (clinical standard): no fever and no clinical symptoms B. (diagnostic criteria) PCR test results are negative twice every 24 hours For health donors: 1. Those who consent 2. Aged 20 to 65 years old 3. Those who do not have any fever or respiratory symptoms 4. Negative for Anti-SARS-CoV-2 Ab IgG antibodies

Exclusion criteria

Exclusion criteria: 1. Those who do not consent 2. Those under 20 or over 65 years of age 3. Positive for Anti-SARS-CoV-2 IgG antibodies 4. Positive for HIV, syphilis or hepatitis B and C carriers. 5. Those with any active infections requiring systemic medical treatment 6. Those who have been diagnosed with any other serious diseases

Design outcomes

Primary

MeasureTime frame
Cell number following culture of SARS-CoV-2 virus antigen peptide mixture treated peripheral nucleated cells;Fold expansion following culture of SARS-CoV-2 virus antigen peptide mixture treated peripheral nucleated cells

Secondary

MeasureTime frame
Characterization of cultured cells (Phenotypical analysis of cultured cells through flow cytometry)

Countries

Korea, Republic of

Contacts

Public ContactJong Min Lee

The Catholic University of Korea, Seoul St. Mary's Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026