Comparison of postoperative analgesic efficacy of intrathecal morphine and quadratus lumborum block in patients receiving laparoscopic donor hepatectomy

Comparison of postoperative analgesic efficacy of intrathecal morphine and quadratus lumborum block in patients receiving laparoscopic donor hepatectomy; a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0005360

Enrollment

Registered

2020-09-01

Start date

2020-09-20

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug, Procedure/Surgery : In the control group (standard treatment group), single intrathecal injection of 0.4mg of morphine sulfate is performed at the L3-L4 or L4-L5 level with a 27G whitacre spinal

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Patients who received living donor hepatectomy for liver transplantation - ASA Physical status I or II : example) healthy adults without underlying disease (I), Mild diseases only without substantive functional limitations. Examples include well-controlled HTN/DM etc.(II)

Exclusion criteria

Exclusion criteria: - ASA physical status III or more : ex) a patient with severe systemic disease like uncontrolled DM(III), a patient with severe systemic disease that is a constant threat to life (IV), a moribund patient who is not expected to survive without the operation - Pregnant women - Severe impaired coagulation profile (equal or more than INR 1.5 last coagulation test before the surgery) - Patients who have unstable coronary disease or Congestive heart failure or Arrythmia or cardiomyopathy - Patients who have cerebrovascular disease - Patients who have systemic infection or local Infection on lumbar or flank area - Chronic pain patients - Patients who don't understand about study or refuse the study - Patients who have allergy for local anesthetics - Patients who have history of severe psychological disease

Design outcomes

Primary

Measure	Time frame
Pain score (representing by 11-points Numerous Rating Scale)	—

Secondary

Measure	Time frame
Pain score (representing by 11-points Numerous Rating Scale);Pain score (representing by 11-points Numerous Rating Scale);Opioid consumption;Nausea, Vomiting, Pruritis, Hypoventilation;ropivacaine plasma concentrations;Pain satisfaction;Sleep satisfaction;first gas-out time;Procedure time;Adverse effect about intervention;the questionaire of QoR-15 score before and after the surgery	—

Countries

Korea, Republic of

Contacts

Public ContactJoan Lee

Samsung Medical Center

seungwon0209.lee@samsung.com+82-2-3410-0369

Outcome results