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Multicenter prospective cohort study on the development of benign gallbladder disease and molecular analysis of bile composition in non-alcoholic fatty liver disease

Multicenter prospective cohort study on the development of benign gallbladder disease and molecular analysis of bile composition in non-alcoholic fatty liver disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0005304
Enrollment
780
Registered
2020-08-11
Start date
2020-08-17
Completion date
Unknown
Last updated
2020-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Hanyang University Seoul Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients hospitalized for cholecystectomy due to a benign disease of the gallbladder (gallstone or gallbladder polyp) 2. 19 to 80

Exclusion criteria

Exclusion criteria: 1. For acute cholecystitis, grade II & III of Tokyo guideline 2018 2. In case of acute cholecystitis, hepatitis level is more than 5 times the upper limit of normal. 3. When jaundice level is more than 3 times the normal upper limit due to acute inflammation 4. If there is a tendency to hemorrhage due to prothrombin time less than 50,000 prolonged 1.5 times or more 5. In the past 2 years, alcoholic liver disease is suspected with a weekly alcohol consumption of 210g or more in men and 140g or more in women. 6. A case of liver disease caused by chronic hepatitis B or C 7. If you have a history of taking medications that can cause fatty liver A. Glucocorticoid B. Tamoxifen C. Methotrexate D. Valproate E. Amiodarone F. 5-fluorouracil G. Irinotecan H. Highly active antiretroviral therapy (HARRT) 8. If you have a genetic disease that causes fatty liver A. Abetalipoproteinemia B. Familial hypobetalipoproteinemia C. Familial combined hyperlipidemia D. Glycogen storage disease E. Lipodystrophy F. Weber-Christian disease

Design outcomes

Primary

MeasureTime frame
Biomarker

Secondary

MeasureTime frame
Bile acid composition

Countries

Korea, Republic of

Contacts

Public ContactDeawon Jun

Hanyang University

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026