Production of placenta derived decidual stromal cells for clinical use

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0005291

Enrollment

120

Registered

2020-08-04

Start date

2020-07-13

Completion date

Unknown

Last updated

2020-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Biological/Vaccine, Stem Cell, Others(Human Resource Study- Cell Therapy) : Collection of placental membrane from cesarean surgery

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Those who consent to the study 2. Those expecting a cesarean surgery

Exclusion criteria

Exclusion criteria: 1. Those who do not consent 2. Those with genetic diseases or chromosomal abnormalities 3. Positive for HIV antibody or hepatitis B and C carriers 4. Positive for syphillis

Design outcomes

Primary

Measure	Time frame
Culturing and inducing DSCs from the placental decidual membrane	—

Secondary

Measure	Time frame
Evaluating the fold expansion of DSCs;Evaluating the immunomodulatory capacity of DSCs through analysis of cytokine secretion and imunomodulatory molecules;Evaluating the therapeutic effects of DSCs through treatment of in vivo mouse GVHD model	—

Countries

Korea, Republic of

Contacts

Public ContactHyun Sun Ko

The Catholic University of Korea, Seoul St. Mary's Hospital

Outcome results