A research on the effects of HX-106 on symptom improvement and brain function change in child and adolescent patients with Attention Deficit Hyperactivity Disorder

A research on the effects of HX106 on symptom improvement and brain function change in child and adolescent patients with Attention Deficit Hyperactivity Disorder

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0005285

Enrollment

Registered

2020-08-04

Start date

2018-07-27

Completion date

Unknown

Last updated

2020-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : Experimental Drug: HX-106 Main ingredients: HX106 (A combined herbal extract of Gastrodiae Rhizoma, Longanae Fructus, Liriopes Radix, Salvia Miltiorrhiza Radix) solids 300 mg + d

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) Pediatric patients between 6 and 23 years old (2) Patients that weigh over 25 kg (3) Patients diagnosed with ADHD as per DSM-IV diagnostic criteria or patients diagnosed with ADHD along with coexisting diseases (4) Patients taking Methylphenidate or Atomoxetine (5) IQ 70 or higher (6) Patients who have been thoroughly informed of the details of the study by the researcher/person delegated by the research director and have consented for study participation by the patient and the patient’s guardian.

Exclusion criteria

Exclusion criteria: (1) Patients that did not agree to participate in the study (2) IQ less than 70 (3) Patients with congenital genetic disease, cerebral palsy, or those with a clear history of acquired brain damage (4) Patients diagnosed with a seizure disorder or other neurological disease

Design outcomes

Primary

Measure	Time frame
Resting-State Functional Magnetic Resonance Imaging (rs-fMRI);ADHD Rating Scale (ARS);Beck Depression Inventory (BDI);Barratt Impulsiveness Scale (BIS);Comprehensive Attention Test (CAT);Computerized NeuroCognitive Function test (CNT)	—

Secondary

Measure	Time frame
Korean Wechsler Adult Intelligence Scale (K-WAIS);Korean Wechsler Scale for Children (K-WISC)	—

Countries

Korea, Republic of

Contacts

Public ContactSujin Bae

Chung-Ang University

Outcome results