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Invasive physiologic assessment of Coronary artery stenosis by rEsting Full-cycLe ratio and fractional flOW resERve: a prospective observational study

Invasive physiologic assessment of Coronary artery stenosis by rEsting Full-cycLe ratio and fractional flOW resERve: a prospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0005255
Enrollment
400
Registered
2020-07-24
Start date
2020-10-28
Completion date
Unknown
Last updated
2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Yonsei University Yongin Severance Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Patients, = 19 years of age, who are diagnosed with stable angina pectoris including silent ischemic heart disease and 50~90% stenosis of coronary artery. - Acute coronary syndrome patients with multivessel disease who have 50~90% stenosis of non-culprit vessel on coronary angiography. -Patients who voluntarily decided to participate in this study and consented in writing to the subject consent

Exclusion criteria

Exclusion criteria: - Patients with acute coronary syndrome and single vessel disease - Patients with hypersensitivity or contraindication to antiplatelet treatment - Female of childbearing potential, who possibly plans to become pregnant any time after enrollment into this study. - Patients with a life expectancy shorter than 1 year

Design outcomes

Primary

MeasureTime frame
Comparison of pre-interventional value between RFR and FFR

Secondary

MeasureTime frame
Comparison of pre-interventional value between RFR and FFR;Comparison of post-interventional value between RFR and FFR when RFR/FFR-guided PCI is performed;Measurement of RFR values and comparison of FFR values after administration of nicorandil in coronary arteries

Countries

Korea, Republic of

Contacts

Public ContactDeok-Kyu Cho

Yonsei University Yongin Severance Hospital

chodk123@yuhs.ac+82-31-5189-8755

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 10, 2026