None listed
Conditions
Interventions
None listed
Sponsors
The Catholic University of Korea, Uijeongbu St. Mary’s Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Elderly aged 60 or older who complained consistent cognitive decline and visited hospital for dementia work-ups 2) Subjects who underwent neuropsychological tests and brain MRIs 3) Normal performance on all domains of neuropsychological tests (at least -1 standard deviation) 4) Clinical dementia rating score 0 5) Subjects who can visit hospital and undergo follow up evaluations during the study period 6) Subjects who agreed with the study process
Exclusion criteria
Exclusion criteria: 1) mild cognitive impairment or dementia 2) Other cerebral lesions which can cause cognitive impairments on brain MRI (hydrocephalus, cerebral hemorrhage, strategic infarction, tumor) 3) Other neurological disorders except Alzheimer's disease such as Huntington's disease, Parkinson's disease, epilepsy 4) Subjects with severe hearing impairment who cannot undergo phone-based cognitive tests
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Korean version of Mini-Mental State Examination score change during 48 months (range, 0~30) | — |
Secondary
| Measure | Time frame |
|---|---|
| blood amyloid beta value (range, 0~ );Clinical dementia rating (CDR) sum of boxes score (range, 0~18);Korean version of Mini-Mental State Examination score (range, 0~30);Home-based cognitive test score (range, 0~30) | — |
Countries
Korea, Republic of
Contacts
Public ContactYunJeong Hong
The Catholic University of Korea, Uijeongbu St. Mary’s Hospital
Outcome results
None listed