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Genomic features of cognitive impairment after surgery

Correlation of miRNA in the cerebrospinal fluid between neurodegenerative diseases and postoperative cognitive dysfunction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0005247
Enrollment
60
Registered
2020-07-22
Start date
2020-09-01
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Inha University Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: ? An external fixation or half hip replacement will be performed for a femur fracture. ? Patients 65 years or older ? If the patient or guardian consents to this study ? ASA classification ? or less

Exclusion criteria

Exclusion criteria: ? patients with degenerative brain disease ? Patients with a history of intracranial disease ? Patients with ASA classification ? or higher ? Patients with hearing impairments who are unable to communicate with researchers ? Patients who do not understand or speak Korean

Design outcomes

Primary

MeasureTime frame
miRNA sequencing profiling—

Secondary

MeasureTime frame
operation time duration/ anesthesia duration;intraoperative fluid/transfusion/blood loss/urine;intraoperative hypotension. vasopressor requirement, hypoxia;Hematocrit change before and after surgery—

Countries

Korea, Republic of

Contacts

Public ContactHyunzu Kim

Inha University Hospital

aneshyunzu@gmail.com+82-32-890-3958

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026