Research on the effectiveness of cognitive training using VR in patients with cognitive decline

Investigations of the effectiveness of computer-assisted cognitive intervention program for elderlies with cognitive decline

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0005243

Enrollment

Registered

2020-07-22

Start date

2019-05-26

Completion date

Unknown

Last updated

2020-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Behavioral : Cognitive training program using VR was conducted twice a week, four weeks, eight times in total. The cognitive training program consists of training various cognitive areas such as memor

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with mild cognitive impairment according to Petersen's criteria (Petersen et al., 1999) or mild neurocognitive disorder according to DSM-5 2. Participants with subjective cognitive decline (Jessen et al. 2014) 3. Age = 60 4. MMSE = 20 5. Individuals with no major lesion on Brain MRI such as intracranial haemorrhage, cerebral, cerebellar, or brainstem infarction, hydrocephalus, traumatic brain injury, severe white matter hyperintensity, tumours, multiple sclerosis, or vasculitis. 6. Individuals who voluntarily agreed to participate in the study

Exclusion criteria

Exclusion criteria: 1. major psychiatric disorders such as major neurocognitive disorder, schizophrenia, bipolar disorder, and depressive disorder other than mild cognitive disorder and mild neurocognitive disorder 2. history of neurodegenerative disorders including Creutzfeldt-Jakob disease, Pick’s disease, Huntington’s disease, Parkinson’s disease, inflammation associated with human immunodeficiency viruses, and syphilis 3. vascular major neurocognitive disorder according to DSM-5 4. history of cerebral infarction within 1 year of the screening 5. participation of other clinical trial including pharmacotherapy within 3 months of the screening 6. participants who are not possible to undergo brain MRI or interview. 7. current major cancer including brain tumor 8. drug or medication abuser 9. Subjects deemed inappropriate by researchers to participate in the study

Design outcomes

Primary

Measure	Time frame
MMSE;digit span test;Boston naming test;Rey-Osterrieth complex figure test, copy;Seoul verbal learnin test;Controlled oral word association test;Stroop test;Trail making test	—

Secondary

Measure	Time frame
Geriatric depression scale;Apathy evaluation scale;Positive and negative affect schedule;Quality of life-Alzheimer's disease;Presence questionnaire;Simulator Sickness Questionnaire	—

Countries

Korea, Republic of

Contacts

Public ContactJae Myeong Kang

Gachon University Gil Medical Center

Outcome results