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Correlation between scar biomechanical properties and skin microbiome in burn patients

Correlation between scar biomechanical properties and skin microbiome in burn patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0005228
Enrollment
500
Registered
2020-07-14
Start date
2020-09-01
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Hallym University Medical Center-Hangang
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.subjects according to the burn degree (n=28 in each group; three groups: second-degree superficial partial-thickness burns, second-degree deep partial-thickness burns, and third-degree burns). 2. patients with completely healed burn wounds and burn patients with hypertrophic scars after 3 months (n=39). 3. patients with a burn injury who complain of pruritus and score 5 points or more on the numerical rating scale even with medication and physical therapy for more than 1 month (n=29).

Exclusion criteria

Exclusion criteria: -If steroids or antibiotics are applied or taken within 2 weeks -Women who are pregnant or lactating and those who may be pregnant -If you have a chronic disease that can affect the skin environment, such as diabetes and skin disease -In case of infection of scar area -Electric burn

Design outcomes

Primary

MeasureTime frame
skin microbiome

Secondary

MeasureTime frame
scar elasticity, trans-epidermal water loss, erythema, melanin, scar thickness;VSS; Vancouver scar scale, POSAS; Patient and observer scar assessment scale;ESR, CRP, IL-6, lipopolysaccharide

Countries

Korea, Republic of

Contacts

Public ContactYoon Soo Cho

Hallym University Medical Center-Hangang

hamays@hanmail.net+82-2-2639-5730

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026