None listed
Conditions
Interventions
Drug : High dose DHA omega-3 group received two capsules of Easyeye Dry®, each containing 300 mg of EPA and 820 mg of DHA, once a daily for 8 weeks. The placebo group received two capsules containing
Sponsors
Pusan National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Age over 19 years of age with symptoms of dry eye syndrome with the meibomian gland dysfunction. The diagnosis of dry eye syndrome was made by a single ophthalmologist based on the guideline proposed by Korean Corneal Disease Study Group (KCDSG). Patients who diagnosed under level III DED without history of consumption of omega-3 dietary supplementation in 3 months were enrolled this trial.
Exclusion criteria
Exclusion criteria: Patients who diagnosed level IV DED by KCDSG guideline, allergic conjunctivitis, severe ocular infection and inflammation were excluded. Past history of ocular surgery in 3 months, systemic (anti-anxiety, anti-histamine, anti-depressant) or topical medications that could affect tear film or meibomian gland function were also excluded. Other exclusion criteria included pregnancy, lactating mothers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| tear break-up time, tear secretion function(SM tube), cornea staining (NEI score) | — |
Secondary
| Measure | Time frame |
|---|---|
| Ocular Surface Disease Index questionnaire (ocular irritation, ocular pain, glare, decreased visual acuity) | — |
Countries
Korea, Republic of
Contacts
Public ContactYeonji Jo
Pusan National University Hospital
Outcome results
None listed