None listed
Conditions
Interventions
None listed
Sponsors
Yonsei University, Wonju Severance Christian Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patient (bronchiectasis) - Adults = 20 years - Presence of past history of bronchiectasis exacerbation or pneumonia (Bronchiectasis exacerbation is defined as an aggravation of respiratory symptoms, such as cough, amount or viscosity of sputum, hemoptysis, and dyspnea, for which additional treatment is necessary. - Absence of past history of pneumococcal vaccination or 5 years later since pneumococcal vaccination Healthy controls - Adults without bronchiectasis - Asymptomatic patients present with simple benign lung nodule - Not being treated for chronic liver, kidney, lung or cancer - Including subjects who do not meet the indication of pneumococcal vaccination
Exclusion criteria
Exclusion criteria: - Uncontrolled asthma, COPD - Current treatment for active tuberculosis, lung cancer or interstitial lung disease - Current treatment for bronchiectasis exacerbation - Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of proportion of IgGSD and SAD between patients with bronchiectasis and healthy controls. | — |
Secondary
| Measure | Time frame |
|---|---|
| Analysis of sputum cytokine in patients with humoral immune deficiency in comparison to those without humoral immune deficiency;Analysis of clinical characteristics of patients with humoral immune deficiency in comparison to those without humoral immune deficiency | — |
Countries
Korea, Republic of
Contacts
Public ContactJi-Ho Lee
Yonsei University, Wonju Severance Christian Hospital
Outcome results
None listed