Identification of anti-tumor effect of propofol using microRNA profile analysis in patients undergoing lung cancer surgery

Identification of anti-tumor effect of propofol using next generation sequencing for microRNA profile analysis in patients undergoing lung cancer surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0005192

Enrollment

Registered

2020-07-01

Start date

2020-07-13

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug, Procedure/Surgery : Upon arrival at the operating room, patients&#39

electrocardiogram, peripheral oxygen saturation (SpO2), non-invasive arterial pressure and bispectral index(BIS) are monitored. General anesthesia is induced and maintained with propofol and remifent

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA(american society of anesthesiologists) physical status I-III patients who was diagnosed with non small cell lung cancer stage I or II and age >20

Exclusion criteria

Exclusion criteria: uncontrolled obstructive lung disease and cerebrovascular disease, receiving medication affecting the central nervous system, in the presence of another primary cancer, severe organ dysfunction(liver, renal), chronic inflammatory or autoimmune disorders and nonconsent

Design outcomes

Primary

Measure	Time frame
microRNA profile	—

Secondary

Measure	Time frame
miRNA gene ontology	—

Countries

Korea, Republic of

Contacts

Public ContactKwon Hui Seo

Hallym University Medical Center

Outcome results