None listed
Conditions
Interventions
None listed
Sponsors
Gachon University Gil Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A person who voluntarily decides to participate as a participant and agrees in writing to comply with the precautions after hearing and fully understanding the overall description of this clinical study. 19 years old or older, 60 years old or younger A person determined by the liver transplant center as a living donor for liver transplantation
Exclusion criteria
Exclusion criteria: People under 19 and over 60 Drug abusers In the past 2 years, if the average daily drinking amount exceeded 30g for men (approximately 3 glasses of soju) and 20g for women (approximately 2 glasses of soju) Those who are unable to handle the noise or sequestration environment in the MRI laboratory or who are contraindicated in MRI study (e.g., iron implants or device holders in the body, artificial pacemakers, blood vessel clips, practitioners inserting artifacts into the eyes or ears, and other magnetic effects) Those who have a foreign body that can receive it) History of using drugs that cause secondary fatty liver within the last year (corticosteroids, tamoxifen, amiodarone, methotrexate, etc.) Subjects whose systemic status is judged clinically to be inappropriate for participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between the degrees of steatosis and fibrosis in donor liver before liver transplantation and the degree of regeneration of residual donor liver at 3 months after transplantation | — |
Secondary
| Measure | Time frame |
|---|---|
| Factors related with a delay or an augmentation of liver tissue regeneration 3 months after liver donation surgery as a result of genomic analysis of basal liver tissue;Identification of circulating factors that promote physiological liver tissue regeneration | — |
Countries
Korea, Republic of
Contacts
Public ContactDAE HO LEE
Gachon University Gil Medical Center
Outcome results
None listed