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The study evaluate the efficacy of intraoperative radiotherapy those who underwent neoadjuvant chemotherapy for pancreatic cancer.

A prospective, phase II study evaluating the efficacy of intraoperative radiotherapy after neoadjuvant chemotherapy in patients with resectable pancreatic cancer

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
CRIS
Registry ID
KCT0005113
Enrollment
80
Registered
2020-06-11
Start date
2020-04-27
Completion date
Unknown
Last updated
2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Radiation : The intraoperative radiotherapy is performed which the radiotherapy right after the resection of the tumor.

Sponsors

Yonsei University Health System, Gangnam Severance Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ? Histologic diagnosis or clinically suspected of adenocarcinoma of the pancreas based on imaging tests or tumor markers ? Older than 20 years ? The performance status of patients based ECOG score less than 3 ? Patients with pancreatic cancer who were either surgically resectable or borderline resectable or can be resected after neoadjuvant chemotherapy because of advanced pancreatic cancer ? Patients who voluntarily decided to participate in this clinical study and signed the written informed consent

Exclusion criteria

Exclusion criteria: ? Previous history of irradiation in abdomen ? The treatment site could not be included in the appropriate radiation field, as judged by the radiation oncologist or the surgeon ? In case of distant metastasis ? A systemic condition that, under the judgment of the attending physician, would be difficult for surgery or radiation

Design outcomes

Primary

MeasureTime frame
Local recurrence rate

Secondary

MeasureTime frame
Acute, chronic toxicity;Disease free survival;Overall survival

Countries

Korea, Republic of

Contacts

Public Contactikjae lee

Yonsei University Health System, Gangnam Severance Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026